Coagulation panel

The thrombophilia risk panel is performed on patients suspected of having inherited risks for hypercoagulation.  Testing is performed using a multiplex platform that tests for all four thrombophilia related genetic markers: Factor V Leiden (R506Q mutation), Factor II/Prothrombin (G20210A mutation) and methylene tetrahydrofolate reductase (MTHFR) (C677T and A1298C mutations).

Specimen required:  5 mL whole peripheral blood at 2-8oC.  Frozen specimens are unacceptable.

Reported: Turnaround time for this assay is 2-7 days.

CPT Code(s):  83891, 83892, 83900, 83901×2, 83896×8, 83912

TEST NAME: THROMBOPHILIA RISK PANEL (HPYERCOAG PANEL, COAG RISK PANEL)
METHODOLOGY: Multiplex Polymerase Chain Reaction/ Fluorescence Monitoring (GenMark Dx eSensor),
PERFORMED: Monday- Friday. After hours and weekends: see table of contents for “directory” section
SPECIMEN COLLECTION SUPPLIES: One purple EDTA tube- includes 4 mutations: Factor V Leiden (R506Q), Prothrombin (G20210A), 2 MTHFR mutations (C677T, A1298C).  Panel recommended but individual may be ordered  as clinically indicated.
SPECIMEN COLLECTION: Venous blood draw
HANDLING: Whole blood room temperature, on weekend store in refrigerator
SPECIMEN REQUIREMENTS: Preferred: 3 ml  whole blood
Minimum: 1 ml whole blood
TRANSPORT: Inside biohazard bag
REJECTION CRITERIA: Frozen. Wrong anticoagulant
DEPARTMENT: Molecular Diaganostics & Cytogenetics