The thrombophilia risk panel is performed on patients suspected of having inherited risks for hypercoagulation. Testing is performed using a multiplex platform that tests for all four thrombophilia related genetic markers: Factor V Leiden (R506Q mutation), Factor II/Prothrombin (G20210A mutation) and methylene tetrahydrofolate reductase (MTHFR) (C677T and A1298C mutations).
Specimen required: 5 mL whole peripheral blood at 2-8oC. Frozen specimens are unacceptable.
Reported: Turnaround time for this assay is 2-7 days.
CPT Code(s): 83891, 83892, 83900, 83901×2, 83896×8, 83912
|TEST NAME:||THROMBOPHILIA RISK PANEL (HPYERCOAG PANEL, COAG RISK PANEL)|
|METHODOLOGY:||Multiplex Polymerase Chain Reaction/ Fluorescence Monitoring (GenMark Dx eSensor),|
|PERFORMED:||Monday- Friday. After hours and weekends: see table of contents for “directory” section|
|SPECIMEN COLLECTION SUPPLIES:||One purple EDTA tube- includes 4 mutations: Factor V Leiden (R506Q), Prothrombin (G20210A), 2 MTHFR mutations (C677T, A1298C). Panel recommended but individual may be ordered as clinically indicated.|
|SPECIMEN COLLECTION:||Venous blood draw|
|HANDLING:||Whole blood room temperature, on weekend store in refrigerator|
|SPECIMEN REQUIREMENTS:||Preferred: 3 ml whole blood
Minimum: 1 ml whole blood
|TRANSPORT:||Inside biohazard bag|
|REJECTION CRITERIA:||Frozen. Wrong anticoagulant|
|DEPARTMENT:||Molecular Diaganostics & Cytogenetics|